5-Hydroxyoxindool (standaard)

5-Hydroxyoxindole is a structural analog of uric acid for its antioxidant. 5-Hydroxyoxindole has DPPH radical scavenging activities and lipid peroxidation-inhibitory activities. 5-Hydroxyoxindole is a product of partial metabolism of tryptophan involving conversion in the gut lumen of tryptophan to indole through the action of bacterial tryptophanase and tryptophan synthase. 5-Hydroxyoxindole is one of the main molecules responsible for the neurological symptoms of hepatic encephalopathy in rats. 5-Hydroxyoxindole can be used for the research of oxidative stress-mediated disorders[1][2].

3416-18-0

12352005

Reactive Oxygen Species (ROS)

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Cancer; Metabolic Disease; Neurological Disease

O=C1NC2=C(C=C(O)C=C2)C1

C8H7NO2

149.15

[1]Daisuke Yasuda, et al. Preparation and antioxidant/pro-oxidant activities of 3-monosubstituted 5-hydroxyoxindole derivatives.|[2]Papy-García, D., et al., (2003) . Detection and quantification of 5-hydroxyoxindole in mammalian sera and tissues by high performance liquid chromatography with multi-electrode electrochemical detection. Clinical biochemistry, 36 (3), 215–220.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W001542R/

Reference Standards