5,6,7-Trihydroxy-4'-methoxyflavon

5,6,7-Trihydroxy-4'-methoxyflavone is a flavonoid and a weak inhibitor of xanthine oxidase. 5,6,7-Trihydroxy-4'-methoxyflavone possesses antithrombotic and antioxidant activities. 5,6,7-Trihydroxy-4'-methoxyflavone has an IC50 value of 25.29 µM for DPPH free radical scavenging. 5,6,7-Trihydroxy-4'-methoxyflavone can also inhibit H2O2-induced damage to PC12 cells. 5,6,7-Trihydroxy-4'-methoxyflavone is applicable for the research of diseases such as cerebrovascular disorders[1][2].

6563-66-2

4'-O-Methylscutellarein

12352005

Xanthine Oxidase

Metabolic Enzyme/Protease

Cardiovascular Disease; Neurological Disease

O=C1C=C(C2=CC=C(OC)C=C2)OC3=CC(O)=C(C(O)=C13)O

C16H12O6

300.26

[1]Khan R, et al. Phenolic substances of Caragana conferta and their superoxide scavenging activity. Chemistry of Natural Compounds, 2010, 46 (5) : 722-725.|[2]Shi ZH, et al. Synthesis and biological evaluation of methylated scutellarein analogs based on metabolic mechanism of scutellarin in vivo. Eur J Med Chem. 2015 Dec 1;106:95-105.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N17611/

Natural Products

No Development Reported