![5,7-dichloorpyrazolo[1,5-a]pyrimidine](/_ipx/q_80/productPlaceholder.webp)
5,7-dichloorpyrazolo[1,5-a]pyrimidine
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
5,7-Dichloropyrazolo[1,5-a]pyrimidine (fragment 5) is a pyrazolopyrimidine phosphodiesterase 10A (PDE10A) inhibitor (Ki=24 μM) . 5,7-Dichloropyrazolo[1,5-a]pyrimidine can be used in the study of schizophrenia[1].
57489-77-7
12352005
H302, H315, H319, H335
Phosphodiesterase (PDE)
Metabolic Enzyme/Protease
Neurological Disease
99.75
DMSO : ≥ 200 mg/mL
ClC1=CC(Cl)=NC2=CC=NN21
C6H3Cl2N3
188.01
H302, H315, H319, H335
[1]Raheem IT, et al. Discovery of pyrazolopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Bioorg Med Chem Lett. 2016 Jan 1;26 (1) :126-32.
Room Temperature
Store at room temperature 3 years
http://file.medchemexpress.com/batch_PDF/HY-W003486/5-7-Dichloropyrazolo-1-5-a-pyrimidine-SDS-MedChemExpress.pdf
Reference compound1
No Development Reported
Beschrijving
5,7-Dichloropyrazolo[1,5-a]pyrimidine (fragment 5) is a pyrazolopyrimidine phosphodiesterase 10A (PDE10A) inhibitor (Ki=24 μM) . 5,7-Dichloropyrazolo[1,5-a]pyri
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