5,7,3',4'-Tetramethoxyflavon

5,7,3',4'-Tetramethoxyflavone, an orally active polymethoxyflavones (PMFs) that can be isolated from M. exotica, possesses various bioactivities, including anti-fungal, anti-malarial, anti-mycobacterial, and anti-inflammatory activities. 5,7,3',4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling[1].

855-97-0

12352005

H302, H315, H319, H335

Bacterial; Fungal; Parasite

Anti-infection

COVID-19-immunoregulation

Infection

10mM

99.15

DMSO : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)

O=C1C=C(C2=CC=C(OC)C(OC)=C2)OC3=C1C(OC)=CC(OC)=C3

C19H18O6

342.35

H302, H315, H319, H335

[1]Wu L, et al. 5,7,3',4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling in vivo and in vitro. Biochem Biophys Res Commun. 2014 Sep 26;452 (3) :682-8.|[2]Wu L, et al. 5,7,3',4'-Tetramethoxyflavone protects chondrocytes from ER stress-induced apoptosis through regulation of the IRE1α pathway. Connect Tissue Res. 2018 Mar;59 (2) :157-166. |[3]Wei G, et al. Absolute bioavailability, pharmacokinetics and excretion of 5,7,30 ,40 -tetramethoxyflavone

Room Temperature

4°C (Powder, protect from light)

http://file.medchemexpress.com/batch_PDF/HY-N7030/5-7-3-4-Tetramethoxyflavone-SDS-MedChemExpress.pdf

Natural Products

No Development Reported

Plasmodium