6-Methoxy-8-hydroxyisocumarine-3-carbonzuur

6-Methoxy-8-hydroxyisocoumarin-3-carboxylic acid (Compound MC-1), an isocoumarin, is a metabolite of Cytogenin. 6-Methoxy-8-hydroxyisocoumarin-3-carboxylic acid has anti-angiogenic activity in S-180 implanted dorsal air sac mice model. 6-Methoxy-8-hydroxyisocoumarin-3-carboxylic acid also modifies collagen-induced arthritis. 6-Methoxy-8-hydroxyisocoumarin-3-carboxylic acid can be used for cancers and inflammatory diseases research[1].

39051-96-2

12352100

Endogenous Metabolite

Metabolic Enzyme/Protease

Cancer; Inflammation/Immunology

OC(C=C(C=C1C=C(O2)C(O)=O)OC)=C1C2=O

C11H8O6

236.18

[1]Matsumoto N, et al. Synthesis and biological evaluation of cytogenin derivatives. J Antibiot (Tokyo) . 2001 Mar;54 (3) :285-96.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N16371/

Natural Products

No Development Reported