6-Phosphoglucono-δ-lacton

6-Phosphoglucono-δ-lactone (6-PGδL) is a reversal substrate of glucose-6-phosphate dehydrogenase (G6PD) . 6-Phosphoglucono-δ-lactone is an intermediate compound in the oxidative branch of the pentose phosphate pathway (PPP) . 6-Phosphoglucono-δ-lactone produced from D-glucose-6-phosphate by glucose-6-phosphate dehydrogenase (G6PDH) and is converted to 6-phosphoglutonate by lactonase. 6-Phosphoglucono-δ-lactone can be used for heart failure, type 2 diabetes and cancers research[1][2].

2641-81-8

6-PGδL; 6-Phosphonoglucono-D-lactone

12352005

H302, H315, H319, H335

Endogenous Metabolite; PDI

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Metabolism-sugar/lipid metabolism

Cancer; Metabolic Disease; Cardiovascular Disease

99.0

O=P(O)(O)OC[C@@H]1[C@H]([C@@H]([C@H](C(O1)=O)O)O)O

C6H11O9P

258.12

H302, H315, H319, H335

[1]Preuss J, et al. Identification and characterization of novel human glucose-6-phosphate dehydrogenase inhibitors. J Biomol Screen. 2013 Mar;18 (3) :286-97.

Blue Ice

-20°C (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-W587796/6-Phosphoglucono-δ-lactone-SDS-MedChemExpress.pdf

Reference compound2

No Development Reported