6,7-Dimethyl-5,6,7,8-tetrahydropterine (hydrochloride)

6, 7-dimethyl-5,6,7, 8-Tetrahydropterin hydrochloride is a synthetic analogue of tetrahydro-L-bioterin and is used as a cofactor required for the NOS isoforms, phenylalanine, tyrosine and tryptophan hydroxylases, and other enzymes[1][2].

945-43-7

12352005

H315-H318-H335

Endogenous Metabolite

Metabolic Enzyme/Protease

Others

O=C1N=C(NC2=C1NC(C)C(C)N2)N.Cl

C8H14ClN5O

231.68

P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

[1]Mayer B, et al. In search of a function for tetrahydrobiopterin in the biosynthesis of nitric oxide. Naunyn Schmiedebergs Arch Pharmacol. 1995 May;351 (5) :453-63.|[2]Suckling CJ, et al. 6-Acetyl-7,7-dimethyl-5,6,7,8-tetrahydropterin is an activator of nitric oxide synthases. Bioorg Med Chem Lett. 2008 Mar 1;18 (5) :1563-6.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W071685/

Reference compound1

No Development Reported