680C91
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
A potent and selective inhibitor of tryptophan 2,3-dioxygenase (TDO) Ki=42 nM) 1,2. Displays no activity against indoleamine 2,3-dioxygenase, MAO-A and B and does not effect serotonin uptake. Elevates CSF tryptophan by up to 260% and CSF serotonin by 170% of basal2. TDO inhibition by 680C91 in glioma cells blocked the release of kynurenine, an endogenous tumor promoting AHR ligand4.
Unconjugated
Light brown solid
-20°C
Beschrijving
680C91 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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