7-Hydroxycarbostyril

7-Hydroxycarbostyril (7-Hydroxy-2 (1H) -quinolinone) (Compound 7) is a quinolinone derivative. 7-Hydroxycarbostyril can be used for synthesis of Brexpiprazole. Brexpiprazole, a typical orally active antipsychotic agent, is a partial agonist of human 5-HT1A and dopamine D2L receptor[1].

70500-72-0

7-Hydroxyquinolinone; 2,7-Dihydroxyquinoline

12352005

H302, H315, H319, H335

Drug Derivative

Others

Others

99.98

O=C1NC2=C(C=CC(O)=C2)C=C1

C9H7NO2

161.16

H302, H315, H319, H335

[1]Satheesh D, et al. Novel and facile process for the preparation of Brexpiprazole an antipsychotic drug[J]. Chemical Papers, 2024, 78 (5) : 3017-3022. |[2]Ishima T, et al. Potentiation of neurite outgrowth by brexpiprazole, a novel serotonin-dopamine activity modulator: a role for serotonin 5-HT1A and 5-HT2A receptors. Eur Neuropsychopharmacol. 2015 Apr;25 (4) :505-11.

Room Temperature

Store at room temperature 3 years

http://file.medchemexpress.com/batch_PDF/HY-34763/7-Hydroxycarbostyril-SDS-MedChemExpress.pdf

Reference compound2

No Development Reported