
7-Methyl-guanosine-5'-trifosfaat (dinatrium)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
7-Methyl-guanosine-5'-triphosphate (m7GTP) disodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate disodium phosphorothioate analog is a potent cap-dependent translation inhibitor[1].
104809-18-9
M7GTP (disodium)
12352005
H302
Nucleoside Antimetabolite/Analog
Cell Cycle/DNA Damage
Metabolism-protein/nucleotide metabolism
Metabolic Disease
10 mM in DMSO
CN1C(C2=O)=C(N=C(N)N2)[N+]([C@@H]3O[C@H](COP(OP(OP(O)(O[Na])=O)(O[Na])=O)([O-])=O)[C@@H](O)[C@H]3O)=C1
C11H16N5Na2O14P3
581.17
P264-P270-P330-P501
[1]Kowalska J, et al. Phosphorothioate analogs of m7GTP are enzymatically stable inhibitors of cap-dependent translation. Bioorg Med Chem Lett. 2009 Apr 1;19 (7) :1921-5.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-21586/
Reference compound1
No Development Reported
Beschrijving
7-Methyl-guanosine-5'-triphosphate (m7GTP) disodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate disodium phosphorothioate analog is a potent
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