8-OHdG (DNA/RNA schade) Polyklonale antilichamen
Gecertificeerd

8-OHdG (DNA/RNA schade) Polyklonale antilichamen

Catalog #: bs-1278R-01
Maat: 20 µL

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Technische Documentatie

Technische Specificaties

Background

8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer's disease.

Synonyms

8-Hydroxy-2'-deoxyguanosine; 8-Hydroxydeoxyguanosine; 8 hydroxyguanine; 8 hydroxyguanosine; 8 OHG; 8-OHG; 8OG; 8OHdG; 8OHG

Cellular Locus

Nucleus

Host

• Rabbit

Cross Reactivity

Rat, Species independent

Target

8-OHdG (DNA/RNA Damage)

Clonality

• Polyclonal

Isotype

• IgG

Conjugation

Unconjugated

Source

KLH conjugated 8-OhdG

Applications

ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Cross Reactivity Details

8-OHdG

Beschrijving

8-OHdG (DNA/RNA schade) Polyklonale antilichamen Beschikbaar in 20 µL. Bestel eenvoudig online met snelle levering.

Specificaties

Productnaam8-OHdG (DNA/RNA schade) Polyklonale antilichamen
Categorie
Beschikbare grootte20 µL
Catalogusnummerbs-1278R-01