
8-pCPT-2-O-Me-cAMP-AM
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
A potent, cell-permeable Epac (exchange protein directly activated by cAMP) activator1. Induces RAP1 activation and insulin secretion in pancreatic beta cell lines2-5. Induces vascular relaxation in rat mesenteric artery6. The acetoxymethyl ester confers increased cell-permeability and is cleaved by endogenous esterases to yield the active compound, 8-pCPT-2'-O-Me-cAMP. Addition to cell cultures should be done in serum-free media as esterases in serum will cleave the acetoxymethyl ester and reduce cell permeability.
Unconjugated
Solid
-20°C
Beschrijving
8-pCPT-2-O-Me-cAMP-AM Beschikbaar in 100 µg. Bestel eenvoudig online met snelle levering.
Specificaties
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