9-Fluorenol-d9

9-Fluorenol-d9 (9-Hydroxyfluorene-d9) is the deuterium labeled 9-Fluorenol. 9-Fluorenol (9-Hydroxyfluorene; compound 3) is a dopamine (DAT) inhibitor with IC50 value of 9 μM. 9-Fluorenol is a major metabolite of compound developed as a wake promoting agent. 9-Fluorenol shows wake promotion activity in vivo[1].

9-Hydroxyfluorene-d9

12352005

Dopamine Receptor; Drug Metabolite; Isotope-Labeled Compounds

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling; Others

Neurological Disease

OC1(C2=C(C([2H])=C(C([2H])=C2C3=C1C([2H])=C(C([2H])=C3[2H])[2H])[2H])[2H])[2H]

C13HD9O

191.27

[1]Dunn D, et al. Wake promoting agents: search for next generation modafinil, lessons learned: part III. Bioorg Med Chem Lett. 2012 Jun 1;22 (11) :3751-3.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W751669/

Isotope-Labeled Compounds

No Development Reported