A-438079 HCl
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
A-438079 (899431-18-6) is a competitive P2X7 receptor antagonist (pIC50 = 6.9) .1 Displayed antinociceptive effects in a rat model of neuropathic pain.2 A-438079 prevented the LPS-induced release of IL-1ß and attenuated LPS-induced (via intrathecal lumbar injection) mechanical hyperalgesia in rat hindpaws.3 It prevented mechanical hyperalgesia following peripheral nerve injury.4 A-438079 protected against cerebral ischemia/reperfusion injury in a rat model via reduction of the neuroinflammatory response.5
Unconjugated
White or off-white solid
-20°C
Beschrijving
A-438079 HCl Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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