
A11
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2412926-29-3
Annexin A, Ephrin Receptor
Tyrosine Kinase/Adaptors, GPCR/G Protein
A11 (ANXA1-derived 11 amino acid–long peptide) serves as an inhibitor of the ANXA1-EphA2 interaction, reducing ANXA1 attachment to EphA2 while promoting the association of Cbl (an E3 ubiquitin ligase of EphA2) with EphA2. This peptide also effectively lowers EphA2 levels, greatly enhances EphA2 ubiquitination, and stimulates EphA2 internalization along with the colocalization of EphA2 and Cbl in nasopharyngeal carcinoma (NPC) cells. Moreover, A11 curtails NPC cell proliferation, migration, and invasion, and it suppresses angiogenesis.
[C@H](CC1=CC=C(O)C=C1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(O)=O)=O)CCCCN)=O)CO)=O)CO)=O)CCCCN)=O)[C@@H](C)C)=O)[C@@H](C)O)=O)CCC(N)=O)=O)C(C)C)=O)NC([C@H](CCC(O)=O)N)=O
C53H88N14O19
1225.35
Ice Packs
-20°C
Beschrijving
A11 Beschikbaar in 10 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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