AA43279
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Selective Nav1.1activator. In HEK-293 cells expressing human Nav1.1 channels AA43279 increased the Nav1.1-mediated current in a concentration dependent manner (EC50=9.5 µM) . In rat hippocampal brain slices it increased the firing activity parvalbumin-expressing, fast-spiking GABAergic interneurons and increased the spontaneous inhibitory post-synaptic currents recorded from pyramidal neurons. It displayed anticonvulsant activity in vivo. Important tool compound for exploring the physiology of Nav1.1 channels.1
Unconjugated
Tan solid
-20°C
Beschrijving
AA43279 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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