AAL-993
Gecertificeerd

AAL-993

Catalog #: bs-82021C-01
Maat: 5 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

Background

Inhibits VEGFR-1 (IC50 = 130 nM), VEGFR-2 (IC50 = 23 nM), and VEGFR-3 (IC50 = 18 nM) . PDGFR-ß, cKit, and CSF-1R are also inhibited at higher concentrations (IC50’s 640 nM, 236 nM and 380 nM respectively) . Screening studies have shown no inhibitory activity against a range of other kinases. X-Ray crystallography has shown that AAL-993 binds to the catalytic domain of VEGFR-2 when the protein is in an inactive conformation. Cell permeable, active in vivo and in whole animal studies.

Conjugation

Unconjugated

Buffer

Pale yellow solid

Storage Conditions

RT

Beschrijving

AAL-993 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamAAL-993
Categorie
Beschikbare grootte5 mg
Catalogusnummerbs-82021C-01