Aanbevolen Claudin -1 Monoklonale Antilichaam

Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions.

Claudin-1

O95832

Human

Recombinant human Claudin-1 fragment

UNQ; PRO; CLD; CLDN1; CLD1; ILVASC; SEMP1; claudin-1; Claudin1; CLD 1; CLDN 1; SEMP 1; Senescence associated epithelial membrane protein; Senescence associated epithelial membrane protein 1; Senescence-associated epithelial membrane protein; UNQ481; PRO944; claudin-1; CLD1; ILVASC; SEMP1

A187

Unconjugated

WB; IHC; IP

Signal Transduction

Protein A purified

1 mg/mL

WB 1:500-1:2000; IHC 1:200-1:1000; IP 1:50-1:100

PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Ice bag

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

https://789.bio/eb/l5aXP2OB

22 kDa

18 kDa

IgG, κ