AAV-Cre (AAV-serotype 6) AAV (AAV6-Cre)

This AAV serotype 6 virus (Capsid from AAV6 and ITR from AAV2) expresses Cre Recombinase under the control of a CMV promoter. This Cre contains a nuclear localization signal (NLS) .Cre recombinase is a Type I topoisomerase from P1 bacteriophage that catalyzes site-specific recombination of DNA between loxP sites. loxP is a 34 bp DNA sequence at which confers directionality. Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cultured cells or experimental animals.

AAV-Cre (AAV serotype 6) AAV

41106621

3822190000

Pre-Made

Dry Ice

-80C

12 Months

AAV6-Cre

AAV6

AAV2

Recombinant AAV

CMV (ubiquitous)

PBS/5% Glycerol

1x10^13 GC/ml