AAV-DJ-RFP-iCre AAV (AAVDJ-RFP-iCre)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cells or experimental animals. By applying the mammalian codon usage to Cre recombinase, expression of Cre is improved in the mammalian cells. This improved Cre (iCre) gene also reduce the high CpG content of the prokaryotic coding sequence, thereby reducing the chances of epigenetic silencing in mammals.The AAV-DJ is a synthetic serotype made from DNA family shuffling of 8 wild type serotypes of AAV, including AAV2, 4, 5, 8, 9, avian, bovine and goat AAV. AAV-DJ outperformed standard AAV serotype 1-8 in cultured cells.This AAV-DJ stock expresses an improved Cre (iCre) and a RFP driven by one CMV promoter. The iCre and RFP was separated by a 2A peptides.
AAV-DJ-RFP-iCre AAV
41106621
3822190000
Pre-Made
Dry Ice
-80C
12 Months
AAVDJ-RFP-iCre
AAV-DJ
AAV2
Recombinant AAV
CMV (ubiquitous)
RFP
PBS/5% Glycerol
1x10^13 GC/ml
Beschrijving
Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cells or experimental animals. By app
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