ABCB5 Proteïne, Humaan, Recombinant (Trx)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
0.95
ATP-binding cassette sub-family B member 5 (ABCB5) is a plasma membrane-spanning protein. ABCB5 is principally expressed in physiological skin and human malignant melanoma. ABCB5 has been suggested to regulate skin progenitor cell fusion and mediate chemotherapeutic drug resistance in stem-like tumor cell subpopulations in human malignant melanoma. It is commonly over-expressed on circulating melanoma tumour cells. Furthermore, the ABCB5+ melanoma- initiating cells were demonstrated to express FLT1 (VEGFR1) receptor tyrosine kinase which was functionally required for efficient xenograft tumor formation, as demonstrated by shRNA knockdown experiments.
Ice Packs
-20°C
Beschrijving
ABCB5 Proteïne, Humaan, Recombinant (Trx) Beschikbaar in 5 µg. Bestel eenvoudig online met snelle levering.
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