ABCB7 Antilichaam - C-terminal regio : HRP (ARP43647 P050-HRP)

ATP-binding cassette, sub-family B (MDR/TAP), member 7

ABC7, ASAT, Atm1p, EST140535

22

G3XAC4

NP_001258626

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the C-terminal region of Human ABCB7

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X) (q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

UBC; MRPL10; ATP6V1D; MTCH1; PDCD6; UQCRC1; NDUFB6; APP; PCK1; ICT1; FECH

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

ABCB7 is supported by BioGPS gene expression data to be expressed in COLO205

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 85%; Zebrafish: 92%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

78kDa

Wet Ice

712

ABCB7

ABCB7

Rabbit

ATP-binding cassette sub-family B member 7, mitochondrial Ensembl ENSP00000343849

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