ABD0171
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Flezurafenibum
C04943-1mg
Dehydrogenase
Metabolism
ABD0171 is a potent, irreversible, and selective inhibitor of aldehyde dehydrogenase 1A3 (ALDH1A3), with an IC50 of 0.34 μM using the physiological substrate all-trans-retinaldehyde (atRAL) . It also inhibits ALDH1A2 and ALDH1A1 with IC50 of 0.79 μM and 6.6 μM, respectively. ABD0171 disrupts key oncogenic pathways in triple-negative breast cancer (TNBC) cells in vitro and exhibits robust antitumor and antimetastatic activity in vivo.
Beschrijving
ABD0171 Beschikbaar in 1 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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