ABri

ABri, 34 amino acids long, is an Amyloid subunit with certain degree of N- and C-terminal heterogeneity and no sequence identity to any known amyloid protein. ABri is devoid of glycine, methionine, proline, aspartic acid, tryptophane, tyrosine and glutamine, featuring pyroglutamate at its N-terminus. ABri can be used for cerebral hemorrhages, ischemic infarction and Alzheimer disease research[1].

241145-90-4

12352209

Amyloid-β

Neuronal Signaling

Neurological Disease; Cardiovascular Disease

O=C(NC(C)C(NC(CO)C(NC(CC(N)=O)C(NC(CS)C(NC(CC1=CC=CC=C1)C(NC(C)C(NC(C(C)CC)C(NC(CCCNC(N)=N)C(NC(CC2=CNC=N2)C(NC(CC3=CC=CC=C3)C(NC(CCC(O)=O)C(NC(CC(N)=O)C(NC(CCCCN)C(NC(CC4=CC=CC=C4)C(NC(C)C(NC(C(C)C)C(NC(CCC(O)=O)C(NC(C(O)C)C(NC(CC(C)C)C(NC(C(C)CC)C(NC(CS)C(NC(CO)C(NC(CCCNC(N)=N)C(NC(C(O)C)C(NC(C(C)C)C(NC(CCCCN)C(NC(CCCCN)C(NC(CC(N)=O)C(NC(C(C)CC)C(NC(C(C)CC)C(NC(CCC(O)=O)C(NC(CCC(O)=O)C(NC(CC(N)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(CCC(O)=O)N

C173H277N49O53S2

3955.48

[1]Ghiso J, et al. Cerebral amyloidosis, amyloid angiopathy, and their relationship to stroke and dementia. J Alzheimers Dis. 2001 Feb;3 (1) :65-73.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-P11314/

Peptides

No Development Reported