ABT-737
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
852808-04-9
C07423-5mg
Bcl-2
Apoptosis
CN (C) CCC (CSC1=CC=CC=C1) NC2=C (C=C (C=C2) S (=O) (=O) NC (=O) C3=CC=C (C=C3) N4CCN (CC4) CC5=CC=CC=C5C6=CC=C (C=C6) Cl) [N+] (=O) [O-]
C42H45ClN6O5S2
ABT-737 is a BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM in cell-free assays, respectively; no inhibition observed against Mcl-1, Bcl-B or Bfl-1. ABT-737 induces mitochondrial pathway apoptosis and mitophagy. Phase 2.
2 years -80 in solvent
Beschrijving
ABT-737 Beschikbaar in 5 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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