ABT-869
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
ABT-869 (796967-16-3) ia a structurally novel, potent inhibitor of receptor tyrosine kinases inhibiting VEGFR and PDGFR and related kinases with IC50s= 3, 4, 4, 66, 3 and 14 nM for VEGFR1, VEGFR2, FLT3, PDGFRβ, CSF-1R and KIT respectively.1,2 Protects cells from necroptosis and rescues SIRS mice from TNF-α-induced shock and death.3 Exerts anti-obesity effects by promoting adipocyte browning.4 Inhibits angiogenesis.5
Unconjugated
Off-white solid
-20°C
Beschrijving
ABT-869 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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