Ac-GpYLPQTV-NH2 (acetaat)

Ac-GpYLPQTV-NH2 acetate is a STAT3 inhibitor with an IC50 value of 0.33 μM. Ac-GpYLPQTV-NH2 acetate has antitumor activity[1].

12352209

STAT

JAK/STAT Signaling; Stem Cell/Wnt

Cancer-Kinase/protease

Cancer

99.38

DMSO : 100 mg/mL (ultrasonic)

CC(C)[C@@H](C(N)=O)NC([C@H]([C@H](O)C)NC([C@H](CCC(N)=O)NC([C@H]1N(CCC1)C([C@H](CC(C)C)NC([C@@H](NC(CNC(C)=O)=O)CC2=CC=C(C=C2)OP(O)(O)=O)=O)=O)=O)=O)=O.CC(O)=O.[x]

C38H60N9O14P.xC2H4O2

897.91 (free base)

[1]Uehara Y, et al A. Novel high-throughput screening system for identifying STAT3-SH2 antagonists. Biochem Biophys Res Commun. 2009 Mar 13;380 (3) :627-31.

Blue Ice

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

http://file.medchemexpress.com/batch_PDF/HY-P10201A/Ac-GpYLPQTV-NH2-acetate-SDS-MedChemExpress.pdf

Peptides

No Development Reported

STAT3