Ac-RGDS-NH2
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Ac-RGDS-NH2, a tetrapeptide, is an integrin antagonist. Ac-RGDS-NH2 competitively binds to the GPIIb/IIIa receptor (Ki = 4.2 μM), inhibiting the binding of fibrinogen to platelets and thereby effectively suppressing platelet aggregation. Ac-RGDS-NH2 can be used for research on thrombosis[1].
122207-62-9
12352209
Integrin
Cytoskeleton
Cardiovascular Disease
NC([C@H](CO)NC([C@H](CC(O)=O)NC(CNC([C@@H](NC(C)=O)CCCNC(N)=N)=O)=O)=O)=O
C17H30N8O8
474.47
[1]Samanen J, et al. Development of a small RGD peptide fibrinogen receptor antagonist with potent antiaggregatory activity in vitro. J Med Chem. 1991 Oct;34 (10) :3114-25.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P11416/
Peptides
No Development Reported
Beschrijving
Ac-RGDS-NH2, a tetrapeptide, is an integrin antagonist. Ac-RGDS-NH2 competitively binds to the GPIIb/IIIa receptor (Ki = 4.2 μM), inhibiting the binding of fibr
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