ACADM Antibody - N-terminal regio : HRP (ARP32788_P050-HRP)

Acyl-CoA dehydrogenase, C-4 to C-12 straight chain

MCAD, ACAD1, MCADH

34

P11310

NP_000007

Human, Mouse, Rat, Cow, Horse

The immunogen is a synthetic peptide directed towards the N terminal region of human ACADM

ACADM Is the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Clinical phenotypes are associated with ACADM hereditary deficiency.This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

SUMO2; SUMO3; UBC; MDM2; STRAP; HDAC1; UBD; CUL3; SUMO4; CALM1; USP50; USP20; ACADM

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

ACADM is supported by BioGPS gene expression data to be expressed in 721_B

0.5 mg/ml

Cow: 92%; Horse: 92%; Human: 100%; Mouse: 91%; Rat: 91%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

46kDa

Nichols, M.J., (2008) Am. J. Med. Genet. A 146A (5), 610-619

Wet Ice

421

ACADM

ACADM

Rabbit

Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

NM_000016

AAGFGRCCRVLRSISRFHWRSQHTKANRQREPGLGFSFEFTEQQKEFQAT