Acalabrutinib
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Acalabrutinib (1420477-60-6) is a highly selective, potent (IC50 = 3nM), and irreversible inhibitor of Bruton’s tyrosine kinase (BTK) .1 Improved target selectivity (especially against TEC family kinases and EGFR) decreased the number of serious side effects observed with Ibrutinib.2 Acalabrutinib significantly inhibits BCR signaling, inhibits tumor proliferation, and reduces tumor burden.3 Clinically useful agent for treating B-cell cancers. BTK has also been shown to have a role in modulating the innate immune system, especially in dendritic cells and macrophages, suggesting a possible role in immunotherapy.4
Unconjugated
Yellow solid
-20°C
Beschrijving
Acalabrutinib Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
Recent bekeken producten
Arachis hypogaea Lectin (PNA) - Biotinylated
21510020-1
5mg
1,4- Dioxane Pure
1041330 500
500 mL
Benzonase ELISA Kit
EG23601S
96 Tests
Not I Restriction Enzyme
B2016623
500 Units
K562-HLA-G0101 Overexpressing Cell Line
RG-1214
5x 10^6
Yeast Poly (A) Polymerase
RNT-006-S
30000 Units
Arachis hypogaea lectin (PNA)
05-0116-10mg
10 mg
Anti-APOE2 mouse monoclonal antibody
TD-AB0132
100 µg