Acalabrutinib (ACS-196)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1420477-60-6
C13195-5mg
BTK
Protein Tyrosine Kinase
CC#CC (=O) N1CCCC1C2=NC (=C3N2C=CN=C3N) C4=CC=C (C=C4) C (=O) NC5=CC=CC=N5
C26H23N7O2
Acalabrutinib (ACP-196) is a selective second-generation Bruton's tyrosine kinase (BTK) inhibitor with an IC50 of 3 nM, which prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. ACP-196 has improved target specificity with 323-, 94-, 19- and 9-fold selectivity over the other TEC kinase family members (ITK, TXK, BMX, and TEC, respectively) and no activity against EGFR.
2 years -80 in solvent
Beschrijving
Acalabrutinib (ACS-196) Beschikbaar in 5 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
Specificaties
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