ACAT1 Antilichaam - middengebied: FITC (ARP54277_P050-FITC)

Acetyl-CoA acetyltransferase 1

T2, MAT, ACAT, THIL

38

P24752

NP_000010

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human ACAT1

ACAT1 is a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. The gene encoding ACAT1 spans approximately 27 kb and contains 12 exons interrupted by 11 introns. Defects in this gene are associated with the alpha-methylacetoaceticaciduria disorder, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.

SUMO2; MDM2; ACAT1; VCAM1; ITGA4; AGXT; FLOT1; UBAP2L; TTF2; UBL4A; UQCRFS1P1; UQCRB; SSBP1; SDHB; SDHA; SAFB; MARS; FOXM1; CSE1L; ACO2; TMEM65; TUBB1; TOMM7; TOPBP1; GCN1L1; TIMM44; ACAA2; FBXO6; PEX7; COPS5; CUL1; CUL3; SIRT7; SUMO1; RAD21; UBC; HDAC5

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

IHC, WB

Affinity Purified

ACAT1 is supported by BioGPS gene expression data to be expressed in HepG2

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 92%; Zebrafish: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

41

Wet Ice

427

ACAT1

ACAT1

Rabbit

Acetyl-CoA acetyltransferase, mitochondrial

NM_000019

GHQDVMVAGGMESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIH