ACBI1
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2375564-55-7
C14362-5mg
PROTAC
Others
CC1=C (SC=N1) C2=CC (=C (CNC (=O) C3CC (O) CN3C (=O) C (NC (=O) C4 (F) CC4) C (C) (C) C) C=C2) OCCOC5=CC=C (CN6CCN (CC6) C7=C (N) N=NC (=C7) C8=C (O) C=CC=C8) C=C5
C49H58FN9O7S
ACBI1 is a potent and cooperative PROTAC degrader of SMARCA2, SMARCA4 and PBRM1 with DC50 of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in MV-4-11 cells, respectively. ACBI1 is composed of a bromodomain ligand, a linker, and the E3 ubiquitin ligase VHL. ACBI1 induces anti-proliferative effects and apoptosis.
3 years -20°C powder
Beschrijving
ACBI1 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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MS Solution sufficient for 400 Mini, 142 Midi, 33 Maxi
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Each
MS pipette, variable vol µme 10~100 µL
MSP-100
1 Unit
MS 12-ch pipette, variable vol µme 20~200 µL
MSP-12X200
1 Unit
MS 12-ch pipette, variable vol µme 2~20 µL
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MS Rocking anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
MS-NRK-3001
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MS Orbital Shaker with 30 x 30 cm platform and flat non-slip rubber mat
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MS Reciprocal anti-moistured shaker with 30 x 30 cm platform and flat non-slip rubber mat
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MS pipette, variable vol µme 1000~10000 µL
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