ACC4 (IgG1), Monoklonale Antilichaam

This antibody is an anti-citrullinated protein antibody (ACPA) that, on Collagen alpha-1 (II) chain, binds specifically to citrullinated C1 epitope on alpha-chain (position 359–369) . It cross-reacts with mouse, bovine, and potentially human. Citrullination of proteins is a post-translational modification in which arginine is converted into citrulline by a family of enzymes called peptidylarginine deiminases (PADs) . Proteins are susceptible to citrullination during inflammatory processes, and an autoantibody response to citrullinated proteins is a hallmark of Rheumatoid Arthritis.

This antibody is an anti-citrullinated protein antibody (ACPA) that, on Collagen alpha-1 (II) chain, binds specifically to citrullinated C1 epitope on alpha-chain (position 359–369) . It cross-reacts with mouse, bovine, and potentially...

ACC4 (IgG1), Monoclonal Antibody, 100ug

Antibodies