ACD-antilichaam

This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I.

65057

Q96AP0

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ACD (NP_001075955.1) .

Unconjugated

Primary Antibodies

Other

Affinity purification

HT-29

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 58kDa

IgG

WB: 1:500 - 1:2000

ACD

Mouse liver

Mouse spleen

Mouse testis

Rat liver

ACD shelterin complex subunit and telomerase recruitment factor

Homo sapiens

PIP1, PTOP, TINT1, TPP1, adrenocortical dysplasia protein homolog, POT1 and TIN2-interacting protein, TIN2 interacting protein 1, adrenocortical dysplasia homolog

WB

Liquid