ACER1 Antilichaam - C-terminaal gebied: Biotine (ARP60812 P050-Biotine)

Alkaline ceramidase 1

ASAH3, ALKCDase1

125981

Q8TDN7

NP_597999

Human, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human ACER1

ACER1 hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. It has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. It may have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids.

Biotin

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Cow: 79%; Dog: 92%; Guinea Pig: 75%; Human: 100%; Pig: 85%; Rabbit: 86%; Rat: 77%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

31kDa

Wet Ice

264

ACER1

ACER1

Rabbit

Alkaline ceramidase 1

NM_133492

VNAYALNSIALHILYIVCQEYRKTSNKELRHLIEVSVVLWAVALTSWISD