Acetyl-Histone H3-K4 pAb

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

8290

Q16695

Human, Mouse, Rat

A synthetic acetylated peptide around K4 of human Histone H3 (NP_003484.1) .

Unconjugated

Primary Antibodies

Signal Transduction

Affinity purification

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Acetylated

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

IgG

H3K4ac

Histone cluster 3, H3

Homo sapiens

H3F3A, H3t, H3.4, H3/g, H3FT

WB, IF

Liquid