Acetyltetrapeptide-15

Acetyl tetrapeptide-15 is a synthetic peptide. Acetyl tetrapeptide-15 is derived from endomorphin-2 (Tyr-Pro-Phe-Phe-NH2), a human μ-opioid agonist with selective anti-nociceptive effect. Acetyl tetrapeptide-15 reduces skin hyperreactivity producing inflammatory, chronic and neuropathic pain, by increasing the threshold of neuronal excitability in μ-opioid receptor via an endorphin-like pathway. Acetyl tetrapeptide-15 is used in the cosmetics for sensitive skin[1].

928007-64-1

12352209

Opioid Receptor

GPCR/G Protein; Neuronal Signaling

Neuroscience-Neuromodulation

Neurological Disease

99.49

DMSO : 100 mg/mL (ultrasonic)

O=C([C@@H](NC([C@@H](NC([C@H]1N(CCC1)C([C@@H](NC(C)=O)CC2=CC=C(C=C2)O)=O)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4)N

C34H39N5O6

613.70

[1]Resende DISP, et al. Usage of Synthetic Peptides in Cosmetics for Sensitive Skin. Pharmaceuticals (Basel) . 2021;14 (8) :702.

Blue Ice

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

http://file.medchemexpress.com/batch_PDF/HY-P1626/Acetyl-tetrapeptide-15-SDS-MedChemExpress.pdf

Peptides

No Development Reported

μ Opioid Receptor/MOR