ACHE-IN-23-d10

AChE-IN-23-d10 (4-Amino-Alpha-diethyl amino-o-cresol-d10 (dihydrochloride) ) is the deuterium labeled AChE-IN-23. AChE-IN-23 (compound 3h) is an acetylcholinesterase (AChE) inhibitor with an IC50 value of 48.3 μM[1].

4-Amino-Alpha-diethyl amino-o-cresol-d10 (dihydrochloride)

12352005

Cholinesterase (ChE) ; Isotope-Labeled Compounds

Neuronal Signaling; Others

Neuroscience-Neuromodulation

Neurological Disease

OC1=C(C=C(C=C1)N)CN(C(C([2H])([2H])[2H])([2H])[2H])C(C([2H])([2H])[2H])([2H])[2H].Cl.Cl

C11H10D10Cl2N2O

277.26

[1]Martijn Constantijn de Koning, et al. Discovery of a potent non-oxime reactivator of nerve agent inhibited human acetylcholinesterase. Eur J Med Chem. 2018 Sep 5;157:151-160.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W077226S/

Isotope-Labeled Compounds

No Development Reported