ACMSD Antilichaam

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS) . ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.

130013

Q8TDX5

Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 1-336 of human ACMSD (NP_612199.2) .

Unconjugated

Primary Antibodies

Cancer, Signal Transduction

Affinity purification

Mouse kidney

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 38kDa

IgG

WB: 1:500 - 1:2000

ACMSD

Mouse liver

Rat kidney

Aminocarboxymuconate semialdehyde decarboxylase

Homo sapiens

2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, picolinate carboxylase

WB

Liquid