Acrofolon A
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Acrofolione A is an acetophenone dimer isolated from Acronychia pendunculata with anticancer effects. Acrofolione A induces G0/G1 phase cell cycle arrest and apoptosis in human NALM-6 pre-B cell leukaemia cells. Acrofolione A can be used for leukaemia research[1].
820975-61-9
12352005
Apoptosis; Caspase; PARP; Survivin
Apoptosis; Cell Cycle/DNA Damage; Epigenetics
Cancer-programmed cell death
Cancer
CC(C)CC(C1=C(C(C/C=C(C)\C)=C(C(C(C)=O)=C1O)OC)O)C2=C3C(CC(O3)C(C)(O)C)=C(C(C(C)=O)=C2O)O
C32H42O9
570.67
[1]Matsui T, et al. Acrofolione A and B, acetophenone dimers from Acronychia pendunculata, induce an apoptotic effect on human NALM-6 pre-B cell leukaemia cells. J Pharm Pharmacol. 2019 Mar;71 (3) :348-361.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-N16567/
Natural Products
No Development Reported
Beschrijving
Acrofolione A is an acetophenone dimer isolated from Acronychia pendunculata with anticancer effects. Acrofolione A induces G0/G1 phase cell cycle arrest and ap
Specificaties
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