ACTR1B Antilichaam - middengebied: HRP (ARP52098_P050-HRP)

ARP1 actin-related protein 1 homolog B, centractin beta (yeast)

PC3, ARP1B, CTRN2

10120

P42025

NP_005726

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

The immunogen is a synthetic peptide directed towards the middle region of human ACTR1B

ACTR1B is a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. ACTR1B, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex.

SEH1L; ACTR10; DCTN4; DCTN2; ACTR1A; RABEP1; LMNB1; DCTN3; APP; SMAD6; CUL3; UBC; TK1; MAPK6; CSNK2B; Dctn1; Capza1; CHD3; ACTA1

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB

Affinity Purified

ACTR1B is supported by BioGPS gene expression data to be expressed in HEK293T

0.5 mg/ml

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 77%; Zebrafish: 85%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

42kDa

Wet Ice

376

ACTR1B

ACTR1B

Rabbit

Beta-centractin

NM_005735

VGPARFRAPELLFQPDLVGDESEGLHEVVAFAIHKSDMDLRRTLFANIVL