ADAM17 siRNA (Rat)

SiRNA to inhibit ADAM17 expression using RNA interference

TACE; Disintegrin and metalloproteinase domain-containing protein 17; ADAM 17; TNF-alpha convertase; TNF-alpha-converting enzyme; CD antigen CD156b

R

Synthetic

RNAi

> 97%

Lyophilized powder

We offers pre-designed sets of 3 different target-specific siRNA oligo duplexes of rat ADAM17 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot.

Shipped at 4 °C. Store at -20 °C for one year.

ADAM17 siRNA (Rat) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.

ADAM17

Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.

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