ADAM19 Antilichaam

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has also been demonstrated to be an active metalloproteinase, which may be involved in normal physiological and pathological processes such as cells migration, cell adhesion, cell-cell and cell-matrix interactions, and signal transduction.

8728

Q9H013

Q9H013

Human

This ADAM19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-236 amino acids from the Central region of human ADAM19.

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Signal Transduction

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Batch dependent

Supplied in PBS with 0.09% (W/V) sodium azide.

None

Blue Ice

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

105 kDa

Rabbit Ig

ADAM19

Disintegrin and metalloproteinase domain-containing protein 19

Homo sapiens

Hancock, D.B., et al. Nat. Genet. 42 (1) :45-52 (2010)

Styrkarsdottir, U., et al. Nat. Genet. 41 (1) :15-17 (2009)

Chan, M.W., et al. Neoplasia 10 (9) :908-919 (2008)

Tanabe, C., et al. Biochem. Biophys. Res. Commun. 352 (1) :111-117 (2007)

Disintegrin and metalloproteinase domain-containing protein 19, ADAM 19, 3424-, Meltrin-beta, Metalloprotease and disintegrin dendritic antigen marker, MADDAM, ADAM19, MLTNB

WB, IHC-P, Flow

302393821

Liquid