ADAM22 Antilichaam

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif. This gene is highly expressed in the brain and may function as an integrin ligand in the brain. In mice, it has been shown to be essential for correct myelination in the peripheral nervous system. Alternative splicing results in several transcript variants.

53616

Q9P0K1

Human, Mouse, Rat

Recombinant fusion protein containing a sequence corresponding to amino acids 223-400 of human ADAM22 (NP_004185.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Signal Transduction

Affinity purification

SH-SY5Y

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 100kDa

IgG

WB: 1:1000 - 1:4000

ADAM22

Mouse brain

Mouse kidney

Mouse heart

Rat kidney

Rat heart

ADAM metallopeptidase domain 22

Homo sapiens

ADAM 22, EIEE61, MDC2, disintegrin and metalloproteinase domain-containing protein 22, a disintegrin and metalloproteinase domain 22, metalloproteinase-disintegrin ADAM22-3, metalloproteinase-like, disintegrin-like, and cysteine-rich protein 2

WB

Liquid