ADAMTS2 Antilichaam

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase. This proteinase excises the N-propeptide of the fibrillar procollagens types I-III and type V. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

216725

Human, Mouse, Rat

Recombinant protein of mouse ADAMTS2

Unconjugated

Primary Antibodies

Cancer, Cell Cycle, Signal Transduction

Affinity purification

A375

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 120kDa

IgG

WB: 1:500 - 1:2000

ADAMTS2

U-87MG

THP-1

Rat thymus

A disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2

Mus musculus

ADAM-TS 2, ADAM-TS2, ADAMTS-2, PC I-NP, PCINP, pNPI, A disintegrin and metalloproteinase with thrombospondin motifs 2, a disintegrin and metalloproteinase with thrombospondin repeats, a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2, procollagen I/II amino propeptide-processing enzyme, procollagen N-endopeptidase, procollagen N-proteinase

WB

Liquid