Adenosine Deaminase Monoklonale Antilichaam

Adenosine Deaminase (ADA, adenosine aminohydrolase) is one of the key enzymes of purine nucleotide catabolism. It catalyses the hydrolytic deamination of adenosine and deoxy‑adenosine to inosine and deoxyinosine . ADA is expressed in virtually all tissues and is expressed at high levels in T-lymphocytes. Adenosine Deaminase deficiency can cause a form of SCID (severe combined immunodeficiency) and lymphopenia in both B- and T-cell lineages . ADA can be used as a sensitive diagnostic marker for tuberculous pleuritis . Although it is primarily a cytosolic enzyme, ADA is known to be a positive regulator of T-cell co‑activation due to its binding to CD26 at the cell surface. The interaction of ADA with CD26 regulates lymphocyte-epithelial cell adhesion

ADA

P00813

Human

Recombinant Human Adenosine Deaminase Protein

ADA; adenosine deaminase; adenine deaminase; Adenosine Aminhydrolase; EC 3.5.4.4; ADA1; Adenosine aminohydrolase

9D6

Unconjugated

WB; IP

Epigenetics and Nuclear Signaling; Cancer; Metabolism

Protein A

1 mg/mL

WB 1:500-1:2000; IP 1-5μL/mg of lysate

0.2 μm filtered solution in PBS

Ice bag

This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

https://789.bio/eb/VhkVC2BV

41 kDa

41 kDa

IgG1