Adenosinemonofosfaat3C10,15N5

Adenosine monophosphate-13C10,15N5 (AMP-13C10,15N5) is the 13C- and 15N-labeled Adenosine monophosphate. Adenosine monophosphate is an adenosine A1 receptor agonist. Adenosine monophosphate has significant antiviral activity against HSV-1 and HSV-2. Adenosine monophosphate is a key cellular metabolite regulating energy homeostasis and signal transduction[1][2][3].

AMP-13C10,15N5

12352005

Adenosine Receptor; Endogenous Metabolite; HSV; Isotope-Labeled Compounds

Anti-infection; GPCR/G Protein; Metabolic Enzyme/Protease; Others

COVID-19-anti-virus

Infection

O[13C@@H]1[13C@H](O)[13C@@H]([13CH2]OP(O)(O)=O)O[13C@H]1[15N]2[13CH]=[15N][13C]3=[13C]2[15N]=[13CH][15N]=[13C]3[15NH2]

13C10H14 15N5O7P

362.11

[1]Rittiner JE, et al. AMP is an adenosine A1 receptor agonist. J Biol Chem. 2012 Feb 17;287 (8) :5301-9. |[2]Zhan Y, et al. Adenosine 5'-monophosphate ameliorates D-galactosamine/lipopolysaccharide-induced liver injury through an adenosine receptor-independent mechanism in mice. Cell Death Dis. 2014 Jan 9;5:e985.|[3]Ayisi NK, et al. Comparison of the antiviral effects of 5-methoxymethyldeoxyuridine-5'-monophosphate with adenine arabinoside-5'-monophosphate. Antiviral Res. 1983 Sep;3 (3) :161-74.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-A0181S6/

Isotope-Labeled Compounds

No Development Reported