Adenylaat Kinase 1 (AK1) Mouse Monoclonal Antibody [Kloon ID: LBI5G8]

Adenylate kinase is an enzyme involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate group among adinine nucleotides. Three isozymes of adenylate kinase have been identified in vertebrates, adenylate isozyme 1 (AK1), 2 (AK2) and 3 (AK3) . AK1 is found in the cytosol of skeletal muscle, brain and erythrocytes, whereas AK2 and AK3 are found in the mitochondria of other tissues including liver and heart. AK1 was identified because of its association with a rare genetic disorder causing nonspherocytic hemolytic anemia where a mutation in the AK1 gene was found to reduce the catalytic activity of the enzyme.

Carrier-free (BSA/glycerol-free) AK1 mouse monoclonal antibody, clone LBI5G8

HTL-S-58j

Homo sapiens adenylate kinase 1 (AK1), transcript variant 1, mRNA.

203

P00568

Unconjugated

Metabolic pathways, Purine metabolism

Metabolic pathways, Purine metabolism

WB 1:1000~2000, IF 1:50

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

AK1

https://www.ncbi.nlm.nih.gov/gene/?term=203

https://www.uniprot.org/uniprot/P00568