
ADG-106
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
ADG-106 is a fully human agonistic monoclonal IgG4 antibody against CD137 (4-1BB). ADG-106 has the mechanism to activate CD137 via strong FcγRIIB-mediated crosslinking while antagonizing CD137 ligands. The isotype control for ADG-106 can refer to Human IgG4 (S228P) kappa, Isotype Control.
12352203
TNF Receptor
Apoptosis
Cancer-programmed cell death
Cancer
[ADG-106]
[1]Ma Y, et al. Preclinical characterization and phase 1 results of ADG106 in patients with advanced solid tumors and non-Hodgkin's lymphoma. Cell Rep Med. 2024 Feb 20;5 (2) :101414.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991070/
Inhibitory Antibodies
Phase 2
Beschrijving
ADG-106 is a fully human agonistic monoclonal IgG4 antibody against CD137 (4-1BB). ADG-106 has the mechanism to activate CD137 via strong FcγRIIB-mediated cross
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