ADG-106
Gecertificeerd

ADG-106

Catalog #: HY-P991070
Maat: 1 Each

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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BTW niet inbegrepen
Gratis verzending vanaf €100

Technische Specificaties

Description

ADG-106 is a fully human agonistic monoclonal IgG4 antibody against CD137 (4-1BB). ADG-106 has the mechanism to activate CD137 via strong FcγRIIB-mediated crosslinking while antagonizing CD137 ligands. The isotype control for ADG-106 can refer to Human IgG4 (S228P) kappa, Isotype Control.

UNSPSC

12352203

Target

TNF Receptor

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

[ADG-106]

References & Citations

[1]Ma Y, et al. Preclinical characterization and phase 1 results of ADG106 in patients with advanced solid tumors and non-Hodgkin's lymphoma. Cell Rep Med. 2024 Feb 20;5 (2) :101414.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P991070/

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 2

Beschrijving

ADG-106 is a fully human agonistic monoclonal IgG4 antibody against CD137 (4-1BB). ADG-106 has the mechanism to activate CD137 via strong FcγRIIB-mediated cross

Specificaties

ProductnaamADG-106
Categorie
Beschikbare grootte1 Each
CatalogusnummerHY-P991070